#!/usr/local/bin/perl
use strict;
use warnings;
use Regexp::Assemble;

my $ra = Regexp::Assemble->new;
while(<>){
    chomp;
    next unless $_;
    $ra->add($_);
}
print $ra->re, "\n"
__END__

% grep program /usr/share/dict/words 
program
programist
programistic
programma
programmar
programmatic
programmatically
programmatist
programmer

% grep program /usr/share/dict/words | perl sample.pl 
(?-xism:program(?:m(?:a(?:ti(?:c(?:ally)?|st)|r)?|er)|ist(?:ic)?)?)